Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

An autosomal genetic linkage map of the sheep genome

Journal Article · · Genetics
OSTI ID:110969
; ;  [1]
  1. Univ. of Otago, Dunedin (New Zealand); and others

We report the first extensive ovine genetic linkage map covering 2070 cM of the sheep genome. The map was generated from the linkage analysis of 246 polymorphic markers, in nine three-generation full-sib pedigrees, which make up the AgResearch International Mapping Flock. We have exploited many markers from cattle so that valuable comparisons between these two ruminant linkage maps can be made. The markers, used in the segregation analyses, comprised 86 anonymous microsatellite markers derived from the sheep genome, 126 anonymous microsatellites from cattle, one from deer, and 33 polymorphic markers of various types associated with known genes. The maximum number of informative meioses within the mapping flock was 22. The average number of informative meioses per marker was 140 (range 18-209). Linkage groups have been assigned to all 26 sheep autosomes. 102 refs., 8 figs., 5 tabs.

OSTI ID:
110969
Journal Information:
Genetics, Journal Name: Genetics Journal Issue: 2 Vol. 140; ISSN GENTAE; ISSN 0016-6731
Country of Publication:
United States
Language:
English

Similar Records

Linkage mapping in sheep and deer identifies a conserved pecora ruminant linkage group orthologous to two regions of HSA16 and a portion of HSA7Q
Journal Article · Wed May 01 00:00:00 EDT 1996 · Genomics · OSTI ID:466652

Autosomal dominant familial spastic paraplegia: Tight linkage to chromosome 15q
Journal Article · Thu Sep 01 00:00:00 EDT 1994 · American Journal of Human Genetics · OSTI ID:134013

A high-resolution linkage map of the achondroplasia critical region on human chromosome 4q16.3
Journal Article · Thu Sep 01 00:00:00 EDT 1994 · American Journal of Human Genetics · OSTI ID:134727