Microbial proteomics: the quiet revolution

Journal Article · Sun Jan 01 04:00:00 EST 2012 · CURRENT OPINION IN MICROBIOLOGY

DOI:https://doi.org/10.1016/j.mib.2012.05.004· OSTI ID:1091674

Seraphin, Bertrand ^[1]

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1. University of Strasbourg, France

Technological developments in DNA sequencing and their application to study thousands of microbial genomes or even microbial ecosystems still today often make the headlines of general newspapers and scientific journals. These revolutionary changes are hiding another revolution that is unfolding more quietly in the background: the development of microbial proteomics to study genome expression products. It is important to recognize that while DNA sequencing reveals extensive details about the genomic potential of an organism or community, proteomic measurements reveal the functional gene products that are present and operational under specific environmental conditions, and thus perhaps better characterize the critical biomolecules that execute the life processes (enzymes, signaling, structural factors, etc.).

• Research Organization: Oak Ridge National Laboratory (ORNL)
• Sponsoring Organization: SC USDOE - Office of Science (SC)
• DOE Contract Number: AC05-00OR22725
• OSTI ID: 1091674
• Journal Information: CURRENT OPINION IN MICROBIOLOGY, Journal Name: CURRENT OPINION IN MICROBIOLOGY Journal Issue: 3 Vol. 15; ISSN 1369-5274
• Country of Publication: United States
• Language: English