Systems biology approach to bioremediation

Journal Article · Fri Jun 01 04:00:00 EDT 2012 · Current Opinion in Biotechnology

DOI:https://doi.org/10.1016/j.copbio.2012.01.015· OSTI ID:1082199

Chakraborty, Romy; Wu, Cindy H.; Hazen, Terry C.

Bioremediation has historically been approached as a ‘black box’ in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Finally, understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ‘black box’.

• Research Organization: Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
• Sponsoring Organization: Earth Sciences Division
• DOE Contract Number: AC02-05CH11231
• OSTI ID: 1082199
• Report Number(s): LBNL-5414E
• Journal Information: Current Opinion in Biotechnology, Journal Name: Current Opinion in Biotechnology Journal Issue: 3 Vol. 23; ISSN 0958-1669
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
59 BASIC BIOLOGICAL SCIENCES