Noninvasive Surface Coverage Determination of Chemically Modified Conical Nanopores that Rectify Ion Transport
- Georgia State University, Atlanta
- ORNL
Surface modification will change the surface charge density (SCD) at the signal-limiting region of nanochannel devices. By fitting the measured i V curves in simulation via solving the Poisson and Nernst Planck equations, the SCD and therefore the surface coverage can be noninvasively quantified. Amine terminated organosilanes are employed to chemically modify single conical nanopores. Determined by the protonation deprotonation of the functional groups, the density and polarity of surface charges are adjusted by solution pH. The rectified current at high conductivity states is found to be proportional to the SCD near the nanopore orifice. This correlation allows the noninvasive determination of SCD and surface coverage of individual conical nanopores.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC)
- DOE Contract Number:
- DE-AC05-00OR22725
- OSTI ID:
- 1055185
- Journal Information:
- Analytical Chemistry, Vol. 84, Issue 16; ISSN 0003--2700
- Country of Publication:
- United States
- Language:
- English
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