Preparation and Characterization Challenges to Understanding Environmental and Biological Impacts of Ceria Nanoparticles
It has been increasingly recognized that understanding and predicting the behaviors of nanoparticles is often limited by the degree to which the particles can be reliably produced and are adequately characterized. Examining data from the literature for ceria nanoparticles suggests that thermal history is one factor that has a strong influence on biological impact. Thermal processing may alter many physicochemical properties of the particles including density, crystal structure and the presence of surface contamination, but these may not be sufficiently recorded or reported to determine the ultimate source of an observed impact. A second example shows the types of difficulties that can be encountered in efforts to apply a well-studied synthesis route to producing well defined particles for biological studies. These examples and others highlight the importance of characterizing particles thoroughly and recording details of particle processing and history that are often not recorded and/or reported.
- Research Organization:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 1047371
- Report Number(s):
- PNNL-SA-83765; SIANDQ; 44899; 44751; 44635; 400412000; TRN: US201216%%230
- Journal Information:
- Surface and Interface Analysis, 44(8):881-889, Vol. 44, Issue 8; ISSN 0142-2421
- Country of Publication:
- United States
- Language:
- English
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