Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Lossless droplet transfer of droplet-based microfluidic analysis

Patent ·
OSTI ID:1032987

A transfer structure for droplet-based microfluidic analysis is characterized by a first conduit containing a first stream having at least one immiscible droplet of aqueous material and a second conduit containing a second stream comprising an aqueous fluid. The interface between the first conduit and the second conduit can define a plurality of apertures, wherein the apertures are sized to prevent exchange of the first and second streams between conduits while allowing lossless transfer of droplets from the first conduit to the second conduit through contact between the first and second streams.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
8,061,187
Application Number:
12/430,490
OSTI ID:
1032987
Country of Publication:
United States
Language:
English

References (2)

Sampling and Electrophoretic Analysis of Segmented Flow Streams Using Virtual Walls in a Microfluidic Device journal November 2008
Capillary Electrophoresis Separation in the Presence of an Immiscible Boundary for Droplet Analysis journal October 2006

Similar Records

Robust Extraction Interface for Coupling Droplet-Based and Continuous Flow Microfluidics
Book · Tue Mar 06 23:00:00 EST 2012 · OSTI ID:1056164

Detecting compounds in microfluidic droplets using mass spectrometry
Patent · Tue Jun 02 00:00:00 EDT 2020 · OSTI ID:1650974

Digital microfluidic systems and methods for droplet manipulation
Patent · Mon Nov 08 23:00:00 EST 2021 · OSTI ID:1860039