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Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry

Patent ·
OSTI ID:1032629
 [1];  [2]
  1. Reston, VA
  2. Silver Spring, MD
+ Show Author Affiliations

The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI).

Research Organization:
The George Washington University (Washington, DC)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-01ER15129
Assignee:
The George Washington University (Washington, DC)
Patent Number(s):
8,067,730
Application Number:
12/176,324
OSTI ID:
1032629
Country of Publication:
United States
Language:
English

References (7)

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions journal April 2005
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization journal October 2004
New dimension in nano-imaging: breaking through the diffraction limit with scanning near-field optical microscopy journal November 2004
Direct Protein Detection from Biological Media through Electrospray-Assisted Laser Desorption Ionization/Mass Spectrometry journal May 2006
Nanoscale Atmospheric Pressure Laser Ablation-Mass Spectrometry journal April 2001
Laser Desorption-Atmospheric Pressure Chemical Ionization Mass Spectrometry for the Analysis of Peptides from Aqueous Solutions journal November 2002
Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry journal November 2007

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