Short tandem repeat polymorphism linkage studies in a new family with X-linked mental retardation (MRX20)
Journal Article
·
· American Journal of Medical Genetics
- Robert Wood Johnson Medical School, New Brunswick, NJ (United States); and others
A family with X-linked recessive mental retardation (XLMR) without other obvious manifestations (MRX20) was studied with 14 short tandem repeat polymorphism (STRP) markers. Two-point lod scores above 3 were obtained with DXS1003, DXYS1, DXS3, and DXS458. A multipoint lod score of 4.25 was obtained with peak at DXS1003. Recombination events identify a 55.6 cM interval between DXS1068 and DXS454, while a one unit support interval identifies 40 cM between MAOA and DXS458. 42 refs., 2 figs., 3 tabs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 102890
- Journal Information:
- American Journal of Medical Genetics, Journal Name: American Journal of Medical Genetics Journal Issue: 4 Vol. 57; ISSN 0148-7299; ISSN AJMGDA
- Country of Publication:
- United States
- Language:
- English
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