Experimental activities supporting commercial U.S. accelerator production of 99-Mo

Conference · Fri Jan 01 04:00:00 EST 2010

OSTI ID:1028197

Dale, Gregory E ^[1]; Chemerisov, Sergey D ^[2]; Vandegrift, George F ^[2]

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1. Los Alamos National Laboratory
2. ANL

{sup 99m}Tc, the daughter product of {sup 99}Mo, is the most commonly used radioisotope for nuclear medicine in the U.S. Experiments are being performed at Los Alamos National Laboratory and Argonne National Laboratory to demonstrate production of {sup 99}Mo using accelerators. The {sup 100}Mo({gamma},n){sup 99}Mo reaction in an enriched {sup 100}Mo target is currently under investigation. Three scaled low-power production experiments using a 20-MeV electron linac at Argonne have been performed to date. Two of these experiments used natural Mo targets and produced a total of 613 {mu}C of {sup 99}Mo. The third experiment used an enriched {sup 100}Mo target and produced 10.5 mCi of {sup 99}Mo. Following irradiation the targets were dissolved and the low specific activity solution was processed through an ARSII generator from NorthStar Medical Radioisotopes. Yields of {sup 99m}Tc >95% have been observed.

• Research Organization: Los Alamos National Laboratory (LANL)
• Sponsoring Organization: DOE
• DOE Contract Number: AC52-06NA25396
• OSTI ID: 1028197
• Report Number(s): LA-UR-10-05589; LA-UR-10-5589
• Country of Publication: United States
• Language: English

Related Subjects

43 PARTICLE ACCELERATORS
62 RADIOLOGY AND NUCLEAR MEDICINE
IRRADIATION
ISOTOPE PRODUCTION
LINEAR ACCELERATORS
MEETINGS
MOLYBDENUM 100 TARGET
MOLYBDENUM 99
NUCLEAR MEDICINE
RADIOISOTOPES
RADIOPHARMACEUTICALS
TECHNETIUM 99