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Title: Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.

Abstract

Biological materials generally require stabilization to retain activity or viability in a dry form. A number of industrial products, such as vaccines, probiotics and biopesticides, have been produced as dry preparations. The same methods and materials used for stabilizing commercial microbial products may be applicable to preserving biothreat pathogens in a dry form.

Authors:
; ; ; ; ; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1026611
Report Number(s):
PNNL-SA-77720
Journal ID: ISSN 0039-9140; TLNTA2; 400904030; TRN: US201120%%940
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article
Journal Name:
Talanta, 85(5):2352-2360
Additional Journal Information:
Journal Volume: 85; Journal Issue: 5; Journal ID: ISSN 0039-9140
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; BIOLOGICAL MATERIALS; CARBOHYDRATES; DERIVATIZATION; PATHOGENS; PRESERVATION; PROCESSING; STABILIZATION; VACCINES; VIABILITY; Gas chromatography-mass spectrometry, Matrix-assisted laser desorption/ionization, Carbohydrate additives, Trimethylsilyl derivative

Citation Formats

Wunschel, David S., Wahl, Karen L., Melville, Angela M., Sorensen, Christina M., Colburn, Heather A., Valentine, Nancy B., and Stamper, Casey L. Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.. United States: N. p., 2011. Web. doi:10.1016/j.talanta.2011.07.073.
Wunschel, David S., Wahl, Karen L., Melville, Angela M., Sorensen, Christina M., Colburn, Heather A., Valentine, Nancy B., & Stamper, Casey L. Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.. United States. doi:10.1016/j.talanta.2011.07.073.
Wunschel, David S., Wahl, Karen L., Melville, Angela M., Sorensen, Christina M., Colburn, Heather A., Valentine, Nancy B., and Stamper, Casey L. Fri . "Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.". United States. doi:10.1016/j.talanta.2011.07.073.
@article{osti_1026611,
title = {Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.},
author = {Wunschel, David S. and Wahl, Karen L. and Melville, Angela M. and Sorensen, Christina M. and Colburn, Heather A. and Valentine, Nancy B. and Stamper, Casey L.},
abstractNote = {Biological materials generally require stabilization to retain activity or viability in a dry form. A number of industrial products, such as vaccines, probiotics and biopesticides, have been produced as dry preparations. The same methods and materials used for stabilizing commercial microbial products may be applicable to preserving biothreat pathogens in a dry form.},
doi = {10.1016/j.talanta.2011.07.073},
journal = {Talanta, 85(5):2352-2360},
issn = {0039-9140},
number = 5,
volume = 85,
place = {United States},
year = {2011},
month = {9}
}