Determination of Post-Culture Processing with Carbohydrates by MALDI-MS and TMS derivatization GC/MS.

Journal Article · Fri Sep 30 00:00:00 EDT 2011 · Talanta, 85(5):2352-2360

DOI:https://doi.org/10.1016/j.talanta.2011.07.073· OSTI ID:1026611

Wunschel, David S; Wahl, Karen L; Melville, Angela M; Sorensen, Christina M; Colburn, Heather A; Valentine, Nancy B; Stamper, Casey L

Biological materials generally require stabilization to retain activity or viability in a dry form. A number of industrial products, such as vaccines, probiotics and biopesticides, have been produced as dry preparations. The same methods and materials used for stabilizing commercial microbial products may be applicable to preserving biothreat pathogens in a dry form.

• Research Organization: Pacific Northwest National Laboratory (PNNL), Richland, WA (US)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1026611
• Report Number(s): PNNL-SA-77720; 400904030
• Journal Information: Talanta, 85(5):2352-2360, Journal Name: Talanta, 85(5):2352-2360 Journal Issue: 5 Vol. 85; ISSN 0039-9140; ISSN TLNTA2
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
BIOLOGICAL MATERIALS
CARBOHYDRATES
DERIVATIZATION
Gas chromatography-mass spectrometry
Matrix-assisted laser desorption/ionization
Carbohydrate additives
Trimethylsilyl derivative
PATHOGENS
PRESERVATION
PROCESSING
STABILIZATION
VACCINES
VIABILITY