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Title: Liquid Chromatography-Mass Spectrometry-based Quantitative Proteomics

Journal Article · · Journal of Biological Chemistry, 286(29):25443-25449

Liquid chromatography-mass spectrometry (LC-MS)-based quantitative proteomics has become increasingly applied for a broad range of biological applications due to growing capabilities for broad proteome coverage and good accuracy in quantification. Herein, we review the current LC-MS-based quantification methods with respect to their advantages and limitations, and highlight their potential applications.

Research Organization:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
OSTI ID:
1023115
Report Number(s):
PNNL-SA-76123; JBCHA3; 24698; 400412000; TRN: US201118%%763
Journal Information:
Journal of Biological Chemistry, 286(29):25443-25449, Vol. 286, Issue 29; ISSN 0021-9258
Country of Publication:
United States
Language:
English