A computer system for access to distributed genome mapping data. Progress report
Development of a computer system for access to distributed genome mapping data is continuing. This effort is to develop software which accesses multiple databases and retrieves data which contain information useful for accelerating mapping human chromosomes. For example, the molecular sequence databases (GenBank, EMBL Data Library, PIR, SwissProt) which contain data required for the development of oligonucleotides for probing DNA as well as for extracting data for primer pair development for PCR-based methods. It is also to develop software which qualitatively integrates the following mapping data: (1) markers regionally localized using cytogenetic methods, (2) polymorphic markers ordered by genetic linkage analysis, (3) clones ordered by various ``finger-printing`` methods, (4) fragments ordered by long-range restriction mapping, (5) single genomic fragments or clones that have STSs assigned to them, (6) nucleotide sequences, (7) the associated metadata such as the submitting investigator`s name, location, etc; the source organism; the chromosome the element is from; the chromosomal location is whatever detail is available.
- Research Organization:
- Cold Spring Harbor Lab., NY (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-91ER61190
- OSTI ID:
- 10129309
- Report Number(s):
- DOE/ER/61190-1; ON: DE92008875
- Resource Relation:
- Other Information: PBD: 5 Feb 1992
- Country of Publication:
- United States
- Language:
- English
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