Progress report on hot particle studies

Technical Report · Sat Feb 01 00:00:00 EST 1992

OSTI ID:10125991

Baum, J W; Kaurin, D G; Waligorski, M; Bird, R; Sun, L C ^[1]

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1. Brookhaven National Lab., Upton NY (United States)

NCRP Report 106 on the effects of hot particles on the skin of pigs, monkeys, and humans was critically reviewed and reassessed. The analysis of the data of Forbes and Mikhail on the effects from activated UC{sub 2} particles, ranging in diameter from 144 {mu}m to 328 {mu}m, led to the formulation of a new model to predict both the threshold for acute ulceration and for ulcer diameter. In this model, a point dose of 27 Gy at a depth of 1.33 mm in tissue will cause an ulcer with a diameter determined by the radius to which this dose extends. Application of the model to the Forbes and Mikhail data obtained with mixed fission product beta particles yielded a ``threshold`` (5% probability) of 6 {times} 10{sup 9} beta particles from a point source of high energy (2.25 MeV maximum) beta particles on skin. The above model was used to predict that approximately 1.2 {times} 10{sup 10} beta particles from Sr-Y-90 would produce similar effects, since few Sr-90 beta particles reach 1.33 mm depth. These emissions correspond to doses at 70-{mu}m depth in tissue of approximately 5.3 to 5.5 Gy averaged over 1 cm{sup 2}, respectively.

• Research Organization: Nuclear Regulatory Commission, Washington, DC (United States). Div. of Regulatory Applications; Brookhaven National Lab., Upton, NY (United States)
• Sponsoring Organization: Nuclear Regulatory Commission, Washington, DC (United States)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 10125991
• Report Number(s): NUREG/CR-5725; BNL-NUREG-52287; ON: TI92008637
• Resource Relation: Other Information: PBD: Feb 1992
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
61 RADIATION PROTECTION AND DOSIMETRY
SKIN
BIOLOGICAL RADIATION EFFECTS
SWINE
MONKEYS
HUMAN POPULATIONS
RADIATION DOSES
STRONTIUM 90
DOSE-RESPONSE RELATIONSHIPS
DOSIMETRY
ULCERS
REGRESSION ANALYSIS
PROGRESS REPORT
560161
560162
560101
MAN
ANIMALS, PLANTS, MICROORGANISMS, AND CELLS
DOSIMETRY AND MONITORING