Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source for Elemental Mass Spectrometry
Journal Article
·
· Analytical Chemistry, 83(7):2425-2429
A new, low power ionization source for elemental MS analysis of aqueous solutions is described. The liquid sampling-atmospheric pressure glow discharge (LSAPGD) operates by a process wherein the surface of the liquid emanating from a 75 μm i.d. glass capillary acts as the cathode of the direct current glow discharge. Analytecontaining solutions at a flow rate of 100 μL min-1 are vaporized by the passage of current, yielding gas phase solutes that are subsequently ionized in the < 5 W (maximum of 60 mA and 500 V), ~1 mm3 volume, plasma. The LS-APGD is mounted in place of the normal electrospray ionization source of a Thermo Scientific Exactive orbitrap mass spectrometer system. Basic operating characteristics are described, including the role of discharge power on mass spectral composition, the ability to obtain ultra-high resolution elemental isotopic patterns, and preliminary limits of detection attainable based on the injection of aliquots of multielement standards. While much optimization remains, it is believed that the LS-APGD may present a practical alternative to high-powered (>1 kW) plasma sources typically employed in elemental mass spectrometry, particularly for those cases where costs, operational overhead, and simplicity considerations are important.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 1011791
- Report Number(s):
- PNNL-SA-77552; KP1704020
- Journal Information:
- Analytical Chemistry, 83(7):2425-2429, Journal Name: Analytical Chemistry, 83(7):2425-2429 Journal Issue: 7 Vol. 83
- Country of Publication:
- United States
- Language:
- English
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