[Mass spectrometric analysis of polycyclic aromatic hydrocarbons adducted to DNA]. Final report
Studies described herein sought and to synthesize PAH-adducted residues of DNA to serve as models for carrying out the mass spectrometric studies; to construct and test a high performance, pulsed ion bombardment, time-of-flight (TOF) mass spectrometer; to initiate an investigation of the efficacy of using thin wire sample holders to increase sensitivity and focused ion beam bombardment to increase ion yield and ion transmission; and to initiate an investigation of sensitivity enhancing matrices for PAH-adducted DNA.
- Research Organization:
- Oregon State Univ., Corvallis, OR (United States). Dept. of Agricultural Chemistry
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG06-88ER60696
- OSTI ID:
- 10112374
- Report Number(s):
- DOE/ER/60696-5; ON: DE94004850; BR: HA0204030/KP0102000
- Resource Relation:
- Other Information: PBD: [1992]
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
37 INORGANIC
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DNA ADDUCTS
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37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
DNA ADDUCTS
MASS SPECTROSCOPY
MASS SPECTROMETERS
DESIGN
BENZOPYRENE
CHRYSENE
LIQUID COLUMN CHROMATOGRAPHY
EPOXIDES
TIME-OF-FLIGHT METHOD
PROGRESS REPORT
560300
400102
CHEMICALS METABOLISM AND TOXICOLOGY
CHEMICAL AND SPECTRAL PROCEDURES