The United States Transuranium and Uranium Registries. Revision 1, [Annual] report, October 1, 1990--April 1992

Technical Report · Tue Sep 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/10108692· OSTI ID:10108692

Kathren, R L

This paper describes the history, organization, activities and recent scientific accomplishments of the United States Transuranium and Uranium Registries. Through voluntary donations of tissue obtained at autopsies, the Registries carry out studies of the concentration, distribution and biokinetics of plutonium in occupationally exposed persons. Findings from tissue analyses from more than 200 autopsies include the following: a greater proportion of the americium intake, as compared with plutonium, was found in the skeleton; the half-time of americium in liver is significantly shorter than that of plutonium; the concentration of actinide in the skeleton is inversely proportional to the calcium and ash content of the bone; only a small percentage of the total skeletal deposition of plutonium is found in the marrow, implying a smaller risk from irradiation of the marrow relative to the bone surfaces; estimates of plutonium body burden made from urinalysis typically exceed those made from autopsy data; pathologists were unable to discriminate between a group of uranium workers and persons without known occupational exposure on the basis of evaluation of microscopic kidney slides; the skeleton is an important long term depot for uranium, and that the fractional uptake by both skeleton and kidney may be greater than indicated by current models. These and other findings and current studies are discussed in depth.

• Research Organization: Washington State Univ., Richland, WA (United States). Health Research and Education Center
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: FG06-92EH89181
• OSTI ID: 10108692
• Report Number(s): USTUR--0001-93; CONF-920444--41; ON: DE94004393; BR: HA0111700/HA0117000
• Country of Publication: United States
• Language: English

Related Subjects

560161
560190
61 RADIATION PROTECTION AND DOSIMETRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMERICIUM
FALLOUT
KIDNEYS
LIVER
MAN
OCCUPATIONAL EXPOSURE
PLUTONIUM
PROGRESS REPORT
RADIATION DOSES
RADIATION PROTECTION
RADIATION PROTECTION STANDARDS
RADIONUCLIDE KINETICS
RESEARCH PROGRAMS
SKELETON
TISSUE DISTRIBUTION
USUR