Microarrays of Biomimetic Cells Formed by the Controlled Synthesis of Carbon Nanofiber Membranes

Journal Article · Thu Jan 01 00:00:00 EST 2004 · Nano Letters

DOI:https://doi.org/10.1021/nl0493702· OSTI ID:1003573

Fletcher, Benjamin L ^[1]; Hullander, Eric D ^[1]; Melechko, Anatoli Vasilievich ^[1]; McKnight, Timothy E ^[1]; Klein, Kate L ^[1]; Hensley, Dale K ^[1]; Morrell, Jennifer L. ^[2]; Simpson, Michael L ^[1]; Doktycz, Mitchel John ^[1]

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1. ORNL
2. University of Tennessee, Knoxville (UTK)

Biological processes are carried out in a small physical volume, the cell, where molecular composition coupled with defined nanometer-scale architecture bring about function. A major challenge inherent in copying this engineering ideal is the fabrication and filling of enclosed membrane structures. Described here is the combination of deterministically grown carbon nanofibers, micromachining techniques, and piezo-based ink jet technology to create cellular mimics. The synthesis, testing, and application of coupled arrays of semipermeable microstructures with defined, sub-nanoliter fluid contents are demonstrated.

• Research Organization: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: DE-AC05-00OR22725
• OSTI ID: 1003573
• Journal Information: Nano Letters, Vol. 4, Issue 10; ISSN 1530--6984
• Country of Publication: United States
• Language: English

Related Subjects

36 MATERIALS SCIENCE
77 NANOSCIENCE AND NANOTECHNOLOGY
CARBON
NANOSTRUCTURES
FIBERS
FABRICATION
MEMBRANES
SYNTHESIS
TESTING
MICROSTRUCTURE
PERMEABILITY