Molecular Characterization of Organic Aerosols Using Nanospray Desorption/Electrospray Ionization-Mass Spectrometry

Journal Article · Fri Oct 01 04:00:00 EDT 2010 · Analytical Chemistry, 82(19):7979–7986

DOI:https://doi.org/10.1021/ac101449p· OSTI ID:1000606

Roach, Patrick J; Laskin, Julia; Laskin, Alexander

Nanospray desorption electrospray ionization (Nano-DESI) combined with high-resolution mass spectrometry (HR/MS) is a promising approach for detailed chemical characterization of atmospheric organic aerosol (OA) collected in laboratory and field experiments. In Nano-DESI analyte is desorbed into a solvent bridge formed between two capillaries and the analysis surface, which enables fast and efficient characterization of OA collected on substrates without special sample preparation. Stable signals achieved using Nano-DESI make it possible to obtain high-quality HR/MS data using only a small amount of material (<10 ng). Furthermore, Nano-DESI enables efficient detection of chemically labile compounds in OA, which is important for understanding chemical aging phenomena.

• Research Organization: Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1000606
• Report Number(s): PNNL-SA-73160; 34503; KP1704020
• Journal Information: Analytical Chemistry, 82(19):7979–7986, Journal Name: Analytical Chemistry, 82(19):7979–7986 Journal Issue: 19 Vol. 82
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
AEROSOLS
AGING
CAPILLARIES
DESORPTION
DETECTION
Environmental Molecular Sciences Laboratory
IONIZATION
MASS SPECTROSCOPY
SAMPLE PREPARATION
SOLVENTS
SPECTROSCOPY
SUBSTRATES