Hermann Muller and Mutations in Drosophila
Geneticist and Nobel prize laureate [Hermann J.] Muller was born and schooled in New York City, receiving an A.B., M.A. and, in 1915, his Ph.D. from Columbia University. His first faculty appointment was at Rice University in Houston, Texas. He then accepted a two-year appointment as instructor at Columbia … . In 1920 … Muller accepted an offer from the University of Texas. In Austin his experiments on fruit flies (Drosophila) first showed that exposure to radiation caused mutation in living organisms. This work would earn Muller the 1946 Nobel Prize in Physiology or Medicine.
Muller applied for and won a Guggenheim fellowship in 1932 and left the U.S. in September to spend a year at the only Drosophila laboratory in Europe which was doing parallel work, Berlin's Kaiser Wilhelm Institute for Brain Research. …Muller [then] accepted a position at the Institute of Genetics in Leningrad. … In December, 1934, he and his research group moved to Moscow. …
After leaving the Soviet Union in September 1937, Muller spent some weeks in Paris at Boris Ephrussi's laboratory before accepting an offer from F.A.E. Crew at the Institute of Animal Genetics in Edinburgh. … [In late 1940, Muller was offered] a temporary position at Amherst College in Massachusetts, an undergraduate liberal-arts college. … [T]hat appointment was ultimately determined to end in June 1945. Following a visit to Bloomington, Indiana, and interviews with zoology department faculty and President Herman B. Wells, Muller was offered an appointment as research professor … . A year after his arrival at Indiana Muller received the Nobel Prize. … Muller remained at Indiana University until his retirement in 1964.
Additional information about Hermann Joseph Muller and his research about exposure to radiation causing mutations in fruit flies ( Drosophila) is available in full-text documents and on the Web.
Advances in Radiation Mutagenesis through Studies on Drosophila; DOE Technical Report; 1958
The Influence of Radiation in Altering the Incidence of Mutations in Drosophila. Progress Report on the Past Twelve Months and Renewal Proposal for the Period September 15, 1960 to September 14, 1961; DOE Technical Report; 1960The Influence of Radiation in Altering the Incidence of Mutations in Drosophila. Report on the Terminal Period, 1963-June 30, 1964; DOE Technical Report; 1965
Additional Web Pages:
Hermann J. Muller Collection EAD, Cold Spring Harbor Laboratory Library & Archives