Instrumentation for biomedical and environmental applications based on microtechnology lessons learned

Conference · Fri Jan 01 00:00:00 EST 1999

DOI:https://doi.org/10.1117/12.350047· OSTI ID:9104

Mariella, Jr., R P

Over the last ten years, LLNL has been developing Microtechnology for instrumentation with applications in the biosciences and environment. In order to build and field high-performance instruments, they have often had to alter their original premises and assumptions, significantly. This meant that they were forced to abandon materials and dimensions that were appealing to them when they began the R and D. Examples include work on silicon-based electrophoresis systems, etched-fluidics for sample/sheath flow nozzles in flow cytometers, and polymerase-chain-reaction thermal-cycling chambers based on silicon-nitride. This presentation discusses these and their work on other devices and instruments.

• Research Organization: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
• Sponsoring Organization: USDOE Office of Defense Programs (DP) (US)
• DOE Contract Number: W-7405-ENG-48
• OSTI ID: 9104
• Report Number(s): UCRL-JC-132754; TRN: AH200122%%249
• Resource Relation: Journal Volume: 3606; Conference: Micro-and Nanofrabricated Structures and Devices for Biomedical and Environmental Applications based on Microtechnology-Lessons Learned, San Jose, CA (US), 01/23/1999--01/29/1999; Other Information: PBD: 1 Jan 1999
• Country of Publication: United States
• Language: English

Related Subjects

42 ENGINEERING
59 BASIC BIOLOGICAL SCIENCES
CELL FLOW SYSTEMS
DIMENSIONS
ELECTROPHORESIS
NOZZLES
POLYMERASE CHAIN REACTION
THERMAL CYCLING