Metabolism and Toxicity of Trace Metals in the Marine Mussel, Mytilus edulis
- Univ. of Maryland, Solomons, MD (United States). Chesapeake Biological Laboratory
Since trace metals such as mercury, cadmium, copper, and zinc can be released to the marine environment as a result of the operation of energy technologies, their potential effects on marine organisms need to be understood. Marine organisms have the capability to respond to metal exposure through acclimatization or adaptation to altered conditions. Mechanisms which may be involved in conferring such capabilities have also been identified. This research project investigated one of these mechanisms, the low molecular weight, metal-building protein MT, in relation to metal toxicity and acclimatization/adaptation. Specific topics included purification and characterization of molluscan MTs; examination of the kinetics of induction of these proteins in response to the above metals; the cellular disposition of metals in relation to induction; and metal-toxicity in relation to induction of metal-binding proteins. Studies were conducted on the bay mussel Mytilus edulis and the American oyster Crassostrea virginica. These efforts were planned to contribute to a better understanding of MTs and their relationship to toxic and adaptive responses in commercially- and ecologically-important marine animals.
- Research Organization:
- Univ. of Maryland, Solomons, MD (United States). Chesapeake Biological Laboratory
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG05-86ER60469
- OSTI ID:
- 5933262
- Report Number(s):
- DOE/ER/60469-4; ON: DE91009633
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
CADMIUM
TOXICITY
COPPER
MERCURY
METALLOTHIONEIN
ENZYME INDUCTION
MUSSELS
BIOLOGICAL ADAPTATION
OYSTERS
ZINC
ANTIBODIES
BIOLOGICAL ACCUMULATION
BIOLOGICAL INDICATORS
BIOLOGICAL LOCALIZATION
CADMIUM 109
DOSE-RESPONSE RELATIONSHIPS
ENVIRONMENTAL EXPOSURE
ENZYME IMMUNOASSAY
PROGRESS REPORT
PURIFICATION
SUBCELLULAR DISTRIBUTION
TOLERANCE
ANIMALS
AQUATIC ORGANISMS
BETA DECAY RADIOISOTOPES
BIOASSAY
CADMIUM ISOTOPES
DISTRIBUTION
DOCUMENT TYPES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
GENE REGULATION
IMMUNOASSAY
INTERMEDIATE MASS NUCLEI
INVERTEBRATES
ISOTOPES
METALLOPROTEINS
METALS
MOLLUSCS
NUCLEI
ORGANIC COMPOUNDS
PROTEINS
RADIOISOTOPES
TRANSITION ELEMENTS
YEARS LIVING RADIOISOTOPES
560300* - Chemicals Metabolism & Toxicology
550200 - Biochemistry