Dynamics of Polymer Nanocapsule Buckling and Collapse Revealed by In Situ Liquid-Phase TEM

Alam, Sardar B.; Soligno, Giuseppe; Yang, Jiwoong; Bustillo, Karen C.; Ercius, Peter; Zheng, Haimei; Whitelam, Stephen; Chan, Emory M.

doi:10.1021/acs.langmuir.2c00432

Title: Dynamics of Polymer Nanocapsule Buckling and Collapse Revealed by In Situ Liquid-Phase TEM

Journal Article · Fri May 27 00:00:00 EDT 2022 · Langmuir

DOI:https://doi.org/10.1021/acs.langmuir.2c00432· OSTI ID:1876844

Alam, Sardar B. ^[1];

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^[4]; Whitelam, Stephen ^[1];

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Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Utrecht University (Netherlands)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Daegu Gyeongbuk Institute of Science and Technology (DGIST) (Korea, Republic of)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States)

Nanocapsules are hollow nanoscale shells that have applications in drug delivery, batteries, self-healing materials, and as model systems for naturally occurring shell geometries. In many applications, nanocapsules are designed to release their cargo as they buckle and collapse, but the details of this transient buckling process have not been directly observed. In this work, we use in situ liquid-phase transmission electron microscopy to record the electron-irradiation-induced buckling in spherical 60-187 nm polymer capsules with ~3.5 nm walls. We observe in real time the release of aqueous cargo from these nanocapsules and their buckling into morphologies with single or multiple indentations. The in situ buckling of nanoscale capsules is compared to ex situ measurements of collapsed and micrometer-sized capsules and to Monte Carlo (MC) simulations. The shape and dynamics of the collapsing nanocapsules are consistent with MC simulations, which reveal that the excessive wrinkling of nanocapsules with ultrathin walls results from their large Föppl-von Kármán numbers around 10⁵. Our experiments suggest design rules for nanocapsules with the desired buckling response based on parameters such as capsule radius, wall thickness, and collapse rate.

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Research Organization:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Scientific User Facilities Division; USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division; European Union (EU)

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1876844

Journal Information:: Langmuir, Vol. 38, Issue 23; ISSN 0743-7463

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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Title: Dynamics of Polymer Nanocapsule Buckling and Collapse Revealed by In Situ Liquid-Phase TEM

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