A decade of exploring the cancer epigenome — biological and translational implications
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September 2011 |
p53 tagged sites from human genomic DNA
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January 1994 |
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
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May 2013 |
p53 functions and cell lines: Have we learned the lessons from the past?
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April 2010 |
An integrated map of p53-binding sites and histone modification in the human ENCODE regions
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February 2007 |
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome
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January 2006 |
To repress or not to repress: This is the guardian's question
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June 2011 |
Parallel Profiling of the Transcriptome, Cistrome, and Epigenome in the Cellular Response to Ionizing Radiation
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May 2014 |
Surfing the p53 network
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November 2000 |
Transcriptional Regulation by P53
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April 2010 |
Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress
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May 2014 |
Live or let die: the cell's response to p53
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August 2002 |
p53 mutations in human cancers
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July 1991 |
Mapping the p53 transcriptome universe using p53 natural polymorphs
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September 2013 |
The Maintenance of Epigenetic States by p53: The Guardian of the Epigenome
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December 2012 |
Distinct p53 genomic binding patterns in normal and cancer-derived human cells
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December 2011 |
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
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November 2007 |
Control of NF- B-dependent Transcriptional Responses by Chromatin Organization
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September 2009 |
Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53
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February 2009 |
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes
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August 2011 |
The Origins and Evolution of the p53 Family of Genes
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December 2009 |
Functions of DNA methylation: islands, start sites, gene bodies and beyond
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May 2012 |
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
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January 2008 |
Different gene regulation strategies revealed by analysis of binding motifs
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October 2009 |
Elaborate security TRAINing to fight against expression of genomic junk
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February 2013 |
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
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July 2007 |
Genome-Wide Profiling of p63 DNA–Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus
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August 2010 |
Myc-binding-site recognition in the human genome is determined by chromatin context
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June 2006 |
The p53MH algorithm and its application in detecting p53-responsive genes
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June 2002 |
eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
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February 2013 |
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
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January 2008 |
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
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June 2011 |
Role of p53 Serine 46 in p53 Target Gene Regulation
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March 2011 |
Multiplex sequencing of paired-end ditags (MS-PET): a strategy for the ultra-high-throughput analysis of transcriptomes and genomes
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July 2006 |
p53 Linear Diffusion along DNA Requires Its C Terminus
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November 2004 |
Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements
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March 2005 |
Crosstalk between c-Jun and TAp73α/β contributes to the apoptosis–survival balance
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March 2011 |
TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade
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May 2014 |
Posttranslational Modification of p53: Cooperative Integrators of Function
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October 2009 |
Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions
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August 2013 |
Molecular Basis for Modulation of the p53 Target Selectivity by KLF4
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October 2012 |
Emergent Sensing of Complex Environments by Mobile Animal Groups
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January 2013 |
CpG islands and the regulation of transcription
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May 2011 |
p53 isoforms can regulate p53 transcriptional activity
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September 2005 |
Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
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March 2012 |
The Tumor Suppressor p53: From Structures to Drug Discovery
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February 2010 |
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis
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July 2012 |
Human DNA methylomes at base resolution show widespread epigenomic differences
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October 2009 |
Impact of Alu repeats on the evolution of human p53 binding sites
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January 2011 |
Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63
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February 2012 |
Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements †
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December 2010 |
Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis
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July 2007 |
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
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October 2009 |
A single-molecule characterization of p53 search on DNA
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December 2010 |
p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy
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August 2010 |
Characterization of genome-wide p53-binding sites upon stress response
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May 2008 |
From adjacent activation in Escherichia coli and DNA cyclization to eukaryotic enhancers: the elements of a puzzle
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November 2014 |
Methylation and deamination of CpGs generate p53-binding sites on a genomic scale
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February 2009 |
Transcription factories: genetic programming in three dimensions
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April 2012 |
ChIP–seq: advantages and challenges of a maturing technology
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September 2009 |
Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization
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November 2012 |
Mechanisms of regulatory diversity within the p53 transcriptional network
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February 2008 |
Mechanisms by which transcription factors gain access to target sequence elements in chromatin
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April 2013 |
Transcriptional control of human p53-regulated genes
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May 2008 |
The effects of transcription factor competition on gene regulation
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January 2013 |
How do site-specific DNA-binding proteins find their targets?
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June 2004 |
Tropical forests and the changing earth system
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November 2005 |
Dissimilar DNA binding by p53 in normal and tumor-derived cells
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December 2011 |
Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response
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June 2014 |
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer
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June 2014 |
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells
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June 2013 |
Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells
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September 2013 |
p53 responsive elements in human retrotransposons
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August 2009 |
Some p53-binding proteins that can function as arbiters of life and death
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March 2006 |
Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells
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April 2012 |
A Comprehensive and High-Resolution Genome-wide Response of p53 to Stress
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July 2014 |
p53 and DNA methylation suppress the TRAIN to cell death
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December 2012 |
The Role of Chromatin during Transcription
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February 2007 |
Definition of a consensus binding site for p53
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April 1992 |
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
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September 2012 |
Redefining the p53 response element
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July 2009 |
Cell Context Dependent p53 Genome-Wide Binding Patterns and Enrichment at Repeats
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November 2014 |
A comparative analysis of DNA methylation across human embryonic stem cell lines
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January 2011 |
p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs
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December 2012 |
Regulation of RNA Polymerase II Transcription by Sequence-Specific DNA Binding Factors
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January 2004 |
Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs
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February 2004 |
p53-mediated AKT and mTOR inhibition requires RFX7 and DDIT4 and depends on nutrient abundance
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December 2021 |
A transcriptionally active DNA-binding site for human p53 protein complexes.
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June 1992 |
Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators
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November 2005 |
Constitutive and induced functions of the p53 gene
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December 2010 |
Chromatin Immunoprecipitation-on-Chip Reveals Stress-Dependent p53 Occupancy in Primary Normal Cells but Not in Established Cell Lines
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December 2008 |
Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis
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January 2005 |
Molecular Basis for Modulation of the p53 Target Selectivity by KLF4
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January 2012 |
p53 and DNA methylation suppress the TRAIN to cell death
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January 2013 |