PARP1 Is a TRF2-associated Poly(ADP-Ribose)Polymerase and Protects Eroded Telomeres
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April 2006 |
A DNA damage checkpoint response in telomere-initiated senescence
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November 2003 |
Experimental and Theoretical Studies on the Selectivity of GGG Triplets toward One-Electron Oxidation in B-Form DNA
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September 1999 |
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase
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January 2006 |
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
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July 2006 |
Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication
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July 2009 |
DNA damage and repair in telomeres: relation to aging.
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January 1995 |
Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae.
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September 1996 |
Senescence Induced by Altered Telomere State, Not Telomere Loss
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March 2002 |
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
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November 1999 |
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end
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June 2005 |
Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress
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January 1999 |
Overlapping Specificities of Base Excision Repair, Nucleotide Excision Repair, Recombination, and Translesion Synthesis Pathways for DNA Base Damage in Saccharomyces cerevisiae
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April 1999 |
Telomere dysfunction as a cause of genomic instability in Werner syndrome
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February 2007 |
Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
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August 2004 |
ReviewThe Defense Mechanisms in Mammalian Cells against Oxidative Damage in Nucleic Acids and their Involvement in the Suppression of Mutagenesis and Cell Death
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May 2004 |
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats
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July 1997 |
A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length
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May 2004 |
The number of vertebrate repeats can be regulated at yeast telomeres by Rap1-independent mechanisms
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April 2003 |
Site-Specific Oxidation at GG and GGG Sequences in Double-Stranded DNA by Benzoyl Peroxide as a Tumor Promoter
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November 1999 |
Mapping of the Hot Spots for DNA Damage by One-Electron Oxidation: Efficacy of GG Doublets and GGG Triplets as a Trap in Long-Range Hole Migration
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November 1998 |
Formamidopyrimidines in DNA: Mechanisms of formation, repair, and biological effects
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December 2008 |
POT1 as a terminal transducer of TRF1 telomere length control
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May 2003 |
Defective Telomere Lagging Strand Synthesis in Cells Lacking WRN Helicase Activity
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December 2004 |
Pot1 Deficiency Initiates DNA Damage Checkpoint Activation and Aberrant Homologous Recombination at Telomeres
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July 2006 |
Repair of Formamidopyrimidines in DNA Involves Different Glycosylases
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December 2005 |
Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G 2 /M arrest and multinucleation
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February 2008 |
Deficiencies in Mouse Myh and Ogg1 Result in Tumor Predisposition and G to T Mutations in Codon 12 of the K-Ras Oncogene in Lung Tumors
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May 2004 |
Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency
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November 2007 |
Checkpoint kinase phosphorylation in response to endogenous oxidative DNA damage in repair-deficient stationary-phase Saccharomyces cerevisiae
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August 2009 |
Control of telomere length by the human telomeric protein TRF1
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February 1997 |
8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site
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March 2004 |
An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres
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July 2005 |
Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells
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July 2004 |
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
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August 1998 |
Site-Specific DNA Damage at the GGG Sequence by UVA Involves Acceleration of Telomere Shortening †
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April 2001 |
NEIL1 excises 3' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1
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August 2005 |
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
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January 2008 |
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
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August 2007 |
Telomere-driven replicative senescence is a stress response
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March 2003 |
Functional links between telomeres and proteins of the DNA-damage response
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August 2004 |
Shelterin: the protein complex that shapes and safeguards human telomeres
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September 2005 |
Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase
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July 2009 |
ORC binding to TRF2 stimulates OriP replication
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June 2006 |
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2
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February 2005 |
Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA.
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August 1992 |
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
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October 2007 |
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres
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October 2008 |
Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs
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January 2008 |
Sequence-specific DNA Cleavage by Fe 2+ -mediated Fenton Reactions Has Possible Biological Implications
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January 1999 |
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging
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July 2008 |
Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast
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November 2009 |
Flap Endonuclease 1 Contributes to Telomere Stability
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April 2008 |
Mutagenesis by 8-oxoguanine: an enemy within
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July 1993 |
Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
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June 1999 |
Base excision repair in yeast and mammals
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June 2000 |
TRF2 Protects Human Telomeres from End-to-End Fusions
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February 1998 |
Switching and Signaling at the Telomere
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September 2001 |
CDC17: An essential gene that prevents telomere elongation in yeast
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August 1985 |
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
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January 2000 |
XRCC1 keeps DNA from getting stranded
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February 2000 |
Tankyrase promotes telomere elongation in human cells
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October 2000 |
DNA Damage Foci at Dysfunctional Telomeres
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September 2003 |
ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes
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December 2003 |
Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication
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July 2009 |
A genome-wide telomere screen in yeast: The long and short of it all
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June 2004 |
The Recombination Protein RAD52 Cooperates with the Excision Repair Protein OGG1 for the Repair of Oxidative Lesions in Mammalian Cells
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June 2009 |
8-Oxoguanine Formation Induced by Chronic UVB Exposure Makes Ogg1 Knockout Mice Susceptible to Skin Carcinogenesis
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July 2005 |
Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids
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January 2006 |