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Title: Method and system for formation and withdrawal of a sample from a surface to be analyzed

Patent ·
OSTI ID:1397242

A method and system for formation and withdrawal of a sample from a surface to be analyzed utilizes a collection instrument having a port through which a liquid solution is conducted onto the surface to be analyzed. The port is positioned adjacent the surface to be analyzed, and the liquid solution is conducted onto the surface through the port so that the liquid solution conducted onto the surface interacts with material comprising the surface. An amount of material is thereafter withdrawn from the surface. Pressure control can be utilized to manipulate the solution balance at the surface to thereby control the withdrawal of the amount of material from the surface. Furthermore, such pressure control can be coordinated with the movement of the surface relative to the port of the collection instrument within the X-Y plane.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
UT-BATTELLE, LLC
Patent Number(s):
9,779,926
Application Number:
14/245,324
OSTI ID:
1397242
Resource Relation:
Patent File Date: 2014 Apr 04
Country of Publication:
United States
Language:
English

References (8)

Multiple sample introduction mass spectrometry patent March 2001
Ultra high throughput sampling and analysis systems and methods patent September 2003
Sampling probe for microarray read out using electrospray mass spectrometry patent October 2004
Film-forming method, film-forming apparatus and liquid film drying apparatus patent-application March 2002
System and method for dispensing liquids patent-application May 2003
Sampling probe for microarray read out using electrospray mass spectrometry patent-application October 2003
Exposure apparatus, exposure method, and device fabrication method patent-application April 2006
Enclosed desorption electrospray ionization patent-application July 2008

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