The antibody approach of labeling blood cells

Conference · Tue Dec 31 00:00:00 EST 1991

OSTI ID:10123225

Srivastava, S C

Although the science of blood cell labeling using monoclonal antibodies directed against specific cellular antigens is still in its early stages, considerable progress has recently been accomplished in this area. The monoclonal antibody approach offers the promise of greater selectivity and enhanced convenience since specific cell types can be labeled in vivo, thus eliminating the need for complex and damaging cell separation procedures. This article focuses on these developments with primary emphasis on antibody labeling of platelets and leukocytes. The advantages and the shortcomings of the recently reported techniques are criticality assessed and evaluated.

• Research Organization: Brookhaven National Lab., Upton, NY (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 10123225
• Report Number(s): BNL-45066; CONF-911299-1; ON: DE92007609
• Resource Relation: Conference: 6. Asian oceanian congress of radiology,New Delhi (India),14-18 Dec 1991; Other Information: PBD: [1991]
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD PLATELETS
LABELLING
LEUKOCYTES
MONOCLONAL ANTIBODIES
LABELLED COMPOUNDS
ANTIGENS
550601
UNSEALED RADIONUCLIDES IN DIAGNOSTICS