Materials and methods for stabilizing nanoparticles in salt solutions

Robinson, David Bruce; Zuckermann, Ronald; Buffleben, George M.

Title: Materials and methods for stabilizing nanoparticles in salt solutions

Patent · Tue Jun 11 00:00:00 EDT 2013

OSTI ID:1084247

Robinson, David Bruce; Zuckermann, Ronald; Buffleben, George M.

Sequence-specific polymers are proving to be a powerful approach to assembly and manipulation of matter on the nanometer scale. Ligands that are peptoids, or sequence-specific N-functional glycine oligomers, allow precise and flexible control over the arrangement of binding groups, steric spacers, charge, and other functionality. We have synthesized short peptoids that can prevent the aggregation of gold nanoparticles in high-salt environments including divalent salt, and allow co-adsorption of a single DNA molecule. This degree of precision and versatility is likely to prove essential in bottom-up assembly of nanostructures and in biomedical applications of nanomaterials.

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Research Organization:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Albuquerque, NM)

Patent Number(s):: 8,461,300

Application Number:: 13/005,250

OSTI ID:: 1084247

Country of Publication:: United States

Language:: English

References (51)

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