Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments

Harper, Jason C.; Carson, Bryan D.; Bachand, George D.; Arndt, William D.; Finley, Melissa R.; Brinker, C. Jeffrey; Edwards, Thayne L.

doi:10.1002/elan.201500359

Title: Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments

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Abstract

Despite significant progress in development of bioanalytical devices cost, complexity, access to reagents and lack of infrastructure have prevented use of these technologies in resource-limited regions. To provide a sustainable tool in the global effort to combat infectious diseases the diagnostic device must be low cost, simple to operate and read, robust, and have sensitivity and specificity comparable to laboratory analysis. Thus, in this mini-review we describe recent work using laser machined plastic laminates to produce diagnostic devices that are capable of a wide variety of bioanalytical measurements and show great promise towards future use in low-resource environments.

Authors:

Harper, Jason C. ^[1]; Carson, Bryan D. ^[1]; Bachand, George D. ^[1]; Arndt, William D. ^[1]; Finley, Melissa R. ^[1]; Brinker, C. Jeffrey ^[1]; Edwards, Thayne L. ^[1]

Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Publication Date:: Tue Jul 14 00:00:00 EDT 2015

Research Org.:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Org.:: USDOE National Nuclear Security Administration (NNSA)

OSTI Identifier:: 1237655

Report Number(s):: SAND-2015-4078J
Journal ID: ISSN 1040-0397; 584060

Grant/Contract Number:: AC04-94AL85000

Resource Type:: Accepted Manuscript

Journal Name:: Electroanalysis

Additional Journal Information:: Journal Volume: 27; Journal Issue: 11; Journal ID: ISSN 1040-0397

Publisher:: Wiley

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION; low-resource environment bioanalytics; laser ablated plastic laminates; electrode arrays; DNA detection; orthogonal biosensor

Citation Formats


                    Harper, Jason C., Carson, Bryan D., Bachand, George D., Arndt, William D., Finley, Melissa R., Brinker, C. Jeffrey, and Edwards, Thayne L. Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments.  United States: N. p., 2015. 
Web.  doi:10.1002/elan.201500359.

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                    Harper, Jason C., Carson, Bryan D., Bachand, George D., Arndt, William D., Finley, Melissa R., Brinker, C. Jeffrey, & Edwards, Thayne L. Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments.  United States.  https://doi.org/10.1002/elan.201500359

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                    Harper, Jason C., Carson, Bryan D., Bachand, George D., Arndt, William D., Finley, Melissa R., Brinker, C. Jeffrey, and Edwards, Thayne L. Tue .  
"Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments".  United States.  https://doi.org/10.1002/elan.201500359.  https://www.osti.gov/servlets/purl/1237655.

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@article{osti_1237655,

  title        = {Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments},

  author       = {Harper, Jason C. and Carson, Bryan D. and Bachand, George D. and Arndt, William D. and Finley, Melissa R. and Brinker, C. Jeffrey and Edwards, Thayne L.},

  abstractNote = {Despite significant progress in development of bioanalytical devices cost, complexity, access to reagents and lack of infrastructure have prevented use of these technologies in resource-limited regions. To provide a sustainable tool in the global effort to combat infectious diseases the diagnostic device must be low cost, simple to operate and read, robust, and have sensitivity and specificity comparable to laboratory analysis. Thus, in this mini-review we describe recent work using laser machined plastic laminates to produce diagnostic devices that are capable of a wide variety of bioanalytical measurements and show great promise towards future use in low-resource environments.},

  doi          = {10.1002/elan.201500359},

  journal      = {Electroanalysis},

  number       = 11,

  volume       = 27,

  place        = {United States},

  year         = {Tue Jul 14 00:00:00 EDT 2015},

  month        = {Tue Jul 14 00:00:00 EDT 2015}

}

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https://doi.org/10.1002/elan.201500359

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