Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material

Pinnaduwage, Lal A; Thundat, Thomas G; Brown, Gilbert M; Hawk, John Eric; Boiadjiev, Vassil I

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A - human necessities
A01 - agriculture
A21 - baking
A22 - butchering
A23 - foods or foodstuffs
A24 - tobacco
A41 - wearing apparel
A42 - headwear
A43 - footwear
A44 - haberdashery
A45 - hand or travelling articles
A46 - brushware
A47 - furniture
A61 - medical or veterinary science
A62 - life-saving
A63 - sports
A99 - subject matter not otherwise provided for in this section
B - performing operations
B01 - physical or chemical processes or apparatus in general
B02 - crushing, pulverising, or disintegrating
B03 - separation of solid materials using liquids or using pneumatic tables or jigs
B04 - centrifugal apparatus or machines for carrying-out physical or chemical processes
B05 - spraying or atomising in general
B06 - generating or transmitting mechanical vibrations in general
B07 - separating solids from solids
B08 - cleaning
B09 - disposal of solid waste
B21 - mechanical metal-working without essentially removing material
B22 - casting
B23 - machine tools
B24 - grinding
B25 - hand tools
B26 - hand cutting tools
B27 - working or preserving wood or similar material
B28 - working cement, clay, or stone
B29 - working of plastics
B30 - presses
B31 - making articles of paper, cardboard or material worked in a manner analogous to paper
B32 - layered products
B33 - additive manufacturing technology
B41 - printing
B42 - bookbinding
B43 - writing or drawing implements
B44 - decorative arts
B60 - vehicles in general
B61 - railways
B62 - land vehicles for travelling otherwise than on rails
B63 - ships or other waterborne vessels
B64 - aircraft
B65 - conveying
B66 - hoisting
B67 - opening, closing {or cleaning} bottles, jars or similar containers
B68 - saddlery
B81 - microstructural technology
B82 - nanotechnology
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C - chemistry
C01 - inorganic chemistry
C02 - treatment of water, waste water, sewage, or sludge
C03 - glass
C04 - cements
C05 - fertilisers
C06 - explosives
C07 - organic chemistry
C08 - organic macromolecular compounds
C09 - dyes
C10 - petroleum, gas or coke industries
C11 - animal or vegetable oils, fats, fatty substances or waxes
C12 - biochemistry
C13 - sugar industry
C14 - skins
C21 - metallurgy of iron
C22 - metallurgy
C23 - coating metallic material
C25 - electrolytic or electrophoretic processes
C30 - crystal growth
C40 - combinatorial technology
C99 - subject matter not otherwise provided for in this section
D - textiles
D01 - natural or man-made threads or fibres
D02 - yarns
D03 - weaving
D04 - braiding
D05 - sewing
D06 - treatment of textiles or the like
D07 - ropes
D10 - indexing scheme associated with sublasses of section d, relating to textiles
D21 - paper-making
D99 - subject matter not otherwise provided for in this section
E - fixed constructions
E01 - construction of roads, railways, or bridges
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F - mechanical engineering
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F05 - indexing schemes relating to engines or pumps in various subclasses of classes f01-f04
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F26 - drying
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F42 - ammunition
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G - physics
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G03 - photography
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G06 - computing
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G12 - instrument details
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H - electricity
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Y02 - technologies or applications for mitigation or adaptation against climate change
Y04 - information or communication technologies having an impact on other technology areas
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Title: Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material

Abstract

A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.

Inventors:

Pinnaduwage, Lal A ^[1]; Thundat, Thomas G ^[1]; Brown, Gilbert M ^[1]; Hawk, John Eric ^[2]; Boiadjiev, Vassil I ^[1]

Knoxville, TN
Olive Branch, MS

Issue Date:: Tue Apr 24 00:00:00 EDT 2007

Research Org.:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 908980

Patent Number(s):: 7207206

Application Number:: 11/059,170

Assignee:: UT-Battelle, LLC (Oak Ridge, TN)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N2291/0224 - Mixtures of three or more liquids
G01N2291/0255 -
G01N2291/0256 - Adsorption, desorption, surface mass change, e.g. on biosensors
G01N2291/0427 - Flexural waves, plate waves, e.g. Lamb waves, tuning fork, cantilever
G01N29/022 - {Fluid sensors based on microsensors, e.g. quartz crystal-microbalance [QCM], surface acoustic wave [SAW] devices, tuning forks, cantilevers, flexural plate wave [FPW] devices
G01N29/036 - by measuring frequency or resonance of acoustic waves
G01N29/2418 - {using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics

Show less

DOE Contract Number:: AC05-00OR22725

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats


                    Pinnaduwage, Lal A, Thundat, Thomas G, Brown, Gilbert M, Hawk, John Eric, and Boiadjiev, Vassil I. Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material.  United States: N. p., 2007. 
        Web.

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                    Pinnaduwage, Lal A, Thundat, Thomas G, Brown, Gilbert M, Hawk, John Eric, & Boiadjiev, Vassil I. Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material.  United States.

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                    Pinnaduwage, Lal A, Thundat, Thomas G, Brown, Gilbert M, Hawk, John Eric, and Boiadjiev, Vassil I. Tue .  
        "Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material".  United States.  https://www.osti.gov/servlets/purl/908980.

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@article{osti_908980,

  title        = {Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material},

  author       = {Pinnaduwage, Lal A and Thundat, Thomas G and Brown, Gilbert M and Hawk, John Eric and Boiadjiev, Vassil I},

  abstractNote = {A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Apr 24 00:00:00 EDT 2007},

  month        = {Tue Apr 24 00:00:00 EDT 2007}

}

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Works referenced in this record:

Photochemical Hydrosilylation of 11-Undecenyltriethylammonium Bromide with Hydrogen-Terminated Si Surfaces for the Development of Robust Microcantilever Sensors for Cr(VI)
journal, February 2005

Boiadjiev, V. I.; Brown, G. M.; Pinnaduwage, L. A.
Langmuir, Vol. 21, Issue 4
https://doi.org/10.1021/la047852n

Polymer brushes via surface-initiated polymerizations
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Edmondson, Steve; Osborne, Vicky L.; Huck, Wilhelm T. S.
Chemical Society Reviews, Vol. 33, Issue 1
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Interactions between dendrimer biocides and bacterial membranes
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Chen, Chris Zhisheng; Cooper, Stuart L.
Biomaterials, Vol. 23, Issue 16
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Molecularly imprinted polymers for biosensor applications
journal, March 1999

Yano, K.
TrAC Trends in Analytical Chemistry, Vol. 18, Issue 3
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Sensitive detection of plastic explosives with self-assembled monolayer-coated microcantilevers
journal, August 2003

Pinnaduwage, L. A.; Boiadjiev, V.; Hawk, J. E.
Applied Physics Letters, Vol. 83, Issue 7
https://doi.org/10.1063/1.1602156

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics
journal, September 1999

Jayasena, Sumedha D.
Clinical Chemistry, Vol. 45, Issue 9
https://doi.org/10.1093/clinchem/45.9.1628

New Organic Materials Suitable for Use in Chemical Sensor Arrays
journal, May 1998

Crooks, Richard M.; Ricco, Antonio J.
Accounts of Chemical Research, Vol. 31, Issue 5
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Organometallic Chemistry on Silicon and Germanium Surfaces
journal, May 2002

Buriak, Jillian M.
Chemical Reviews, Vol. 102, Issue 5
https://doi.org/10.1021/cr000064s

Cross-Reactive Chemical Sensor Arrays
journal, July 2000

Albert, Keith J.; Lewis, Nathan S.; Schauer, Caroline L.
Chemical Reviews, Vol. 100, Issue 7
https://doi.org/10.1021/cr980102w

Detection of Hexavalent Chromium in Ground Water Using a Single Microcantilever Sensor
journal, March 2004

Pinnaduwage, L. A.; Boiadjiev, V. I.; Brown, G. M.
Sensor Letters, Vol. 2, Issue 1
https://doi.org/10.1166/sl.2004.028

Nerve Agents Detection Using a Cu ²⁺ / l -Cysteine Bilayer-Coated Microcantilever
journal, February 2003

Yang, Yuming; Ji, Hai-Feng; Thundat, Thomas
Journal of the American Chemical Society, Vol. 125, Issue 5
https://doi.org/10.1021/ja028181n

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Similar Records

Title: Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material

Abstract

Citation Formats

Photochemical Hydrosilylation of 11-Undecenyltriethylammonium Bromide with Hydrogen-Terminated Si Surfaces for the Development of Robust Microcantilever Sensors for Cr(VI) journal, February 2005

Polymer brushes via surface-initiated polymerizations journal, January 2004

Interactions between dendrimer biocides and bacterial membranes journal, August 2002

Molecularly imprinted polymers for biosensor applications journal, March 1999

Sensitive detection of plastic explosives with self-assembled monolayer-coated microcantilevers journal, August 2003

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics journal, September 1999

New Organic Materials Suitable for Use in Chemical Sensor Arrays journal, May 1998

Organometallic Chemistry on Silicon and Germanium Surfaces journal, May 2002

Cross-Reactive Chemical Sensor Arrays journal, July 2000

Detection of Hexavalent Chromium in Ground Water Using a Single Microcantilever Sensor journal, March 2004

Nerve Agents Detection Using a Cu 2+ / l -Cysteine Bilayer-Coated Microcantilever journal, February 2003

Photochemical Hydrosilylation of 11-Undecenyltriethylammonium Bromide with Hydrogen-Terminated Si Surfaces for the Development of Robust Microcantilever Sensors for Cr(VI)
journal, February 2005

Polymer brushes via surface-initiated polymerizations
journal, January 2004

Interactions between dendrimer biocides and bacterial membranes
journal, August 2002

Molecularly imprinted polymers for biosensor applications
journal, March 1999

Sensitive detection of plastic explosives with self-assembled monolayer-coated microcantilevers
journal, August 2003

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics
journal, September 1999

New Organic Materials Suitable for Use in Chemical Sensor Arrays
journal, May 1998

Organometallic Chemistry on Silicon and Germanium Surfaces
journal, May 2002

Cross-Reactive Chemical Sensor Arrays
journal, July 2000

Detection of Hexavalent Chromium in Ground Water Using a Single Microcantilever Sensor
journal, March 2004

Nerve Agents Detection Using a Cu ²⁺ / l -Cysteine Bilayer-Coated Microcantilever
journal, February 2003