Process for the production of 18F-2-deoxy-2-fluoro-D-glucose
Abstract
Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding .sup.18 F-compound by the reaction of acetyl hypofluorite or the corresponding .sup.18 F-compound with 3,4,6-tri-O-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.
- Inventors:
-
- East Setauket, NY
- Pisa, IT
- Setauket, NY
- Bellport, NY
- Sag Harbor, NY
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 875247
- Patent Number(s):
- H000074
- Application Number:
- 06/469597
- Assignee:
- United States of America as represented by United States ()
- DOE Contract Number:
- AC02-76CH00016
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1983 Feb 24
- Country of Publication:
- United States
- Language:
- English
- Subject:
- statutory invention registration; process; production; 18f-2-deoxy-2-fluoro-d-glucose; 2-deoxy-2-fluoro-d-glucose; corresponding; 18; f-compound; reaction; acetyl; hypofluorite; 6-tri-o-acetyl-d-glucal; followed; hydrolysis; compound; ambient; temperature; ambient temperature; acetyl hypofluorite; /999/
Citation Formats
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., and MacGregor, Robert R. Process for the production of 18F-2-deoxy-2-fluoro-D-glucose. United States: N. p., 1986.
Web.
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., & MacGregor, Robert R. Process for the production of 18F-2-deoxy-2-fluoro-D-glucose. United States.
Shiue, Chyng-Yann, Salvadori, Piero A., Wolf, Alfred P., Fowler, Joanna S., and MacGregor, Robert R. Wed .
"Process for the production of 18F-2-deoxy-2-fluoro-D-glucose". United States. https://www.osti.gov/servlets/purl/875247.
@article{osti_875247,
title = {Process for the production of 18F-2-deoxy-2-fluoro-D-glucose},
author = {Shiue, Chyng-Yann and Salvadori, Piero A. and Wolf, Alfred P. and Fowler, Joanna S. and MacGregor, Robert R.},
abstractNote = {Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding .sup.18 F-compound by the reaction of acetyl hypofluorite or the corresponding .sup.18 F-compound with 3,4,6-tri-O-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1986},
month = {Wed Jan 01 00:00:00 EST 1986}
}
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