Flowmeter for pressure-driven chromatography systems
Abstract
A flowmeter for accurately measuring the flowrate of fluids in high pressure chromatography systems. The flowmeter is a porous bed of a material, the porous bed having a porosity in the range of about 0.1 to 0.6 and a pore size in the range of about 50 nm to 1 .mu.m, disposed between a high pressure pumping means and a chromatography column. The flowmeter is provided with pressure measuring means at both the inlet and outlet of the porous bed for measuring the pressure drop through the porous bed. This flowmeter system provides not only the ability to measure accurately flowrates in the range of .mu.L/min to nL/min but also to provide a signal that can be used for a servo loop or feedback control system for high pressure pumping systems.
- Inventors:
-
- Livermore, CA
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- OSTI Identifier:
- 875105
- Patent Number(s):
- 6532802
- Assignee:
- Sandia National Laboratories (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01F - MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- flowmeter; pressure-driven; chromatography; systems; accurately; measuring; flowrate; fluids; pressure; porous; bed; material; porosity; range; 01; 06; pore; size; 50; nm; mum; disposed; pumping; means; column; provided; inlet; outlet; drop; provides; ability; measure; flowrates; mulmin; nlmin; provide; signal; servo; loop; feedback; control; pore size; chromatography column; pressure pump; porous bed; /73/210/
Citation Formats
Paul, Phillip H, and Arnold, Don W. Flowmeter for pressure-driven chromatography systems. United States: N. p., 2003.
Web.
Paul, Phillip H, & Arnold, Don W. Flowmeter for pressure-driven chromatography systems. United States.
Paul, Phillip H, and Arnold, Don W. Wed .
"Flowmeter for pressure-driven chromatography systems". United States. https://www.osti.gov/servlets/purl/875105.
@article{osti_875105,
title = {Flowmeter for pressure-driven chromatography systems},
author = {Paul, Phillip H and Arnold, Don W},
abstractNote = {A flowmeter for accurately measuring the flowrate of fluids in high pressure chromatography systems. The flowmeter is a porous bed of a material, the porous bed having a porosity in the range of about 0.1 to 0.6 and a pore size in the range of about 50 nm to 1 .mu.m, disposed between a high pressure pumping means and a chromatography column. The flowmeter is provided with pressure measuring means at both the inlet and outlet of the porous bed for measuring the pressure drop through the porous bed. This flowmeter system provides not only the ability to measure accurately flowrates in the range of .mu.L/min to nL/min but also to provide a signal that can be used for a servo loop or feedback control system for high pressure pumping systems.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 2003},
month = {Wed Jan 01 00:00:00 EST 2003}
}