Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof
Abstract
A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4-ylmethyl)trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2-dimethyl-1,3-dioxolan-4ylmethyl)trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).
- Inventors:
-
- Haslett, MI
- East Lansing, MI
- Issue Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- OSTI Identifier:
- 873072
- Patent Number(s):
- 6084131
- Assignee:
- Board of Trustees operating Michigan State University (East Lansing, MI)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
- DOE Contract Number:
- FG02-89ER14029
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- process; preparation; protected; dihydroxypropyl; trialkylammonium; salts; derivatives; particularly; chiral; form; described; particular; 2-dimethyl-1; 3-dioxolan-4-ylmethyl; furthermore; 3-dioxolan-4ylmethyl; trimethylammonium; salt; preferably; lead; l-carnitine; trialkylammonium salts; protected dihydroxypropyl; ammonium salts; ammonium salt; chiral form; dihydroxypropyl trialkylammonium; /999/
Citation Formats
Hollingsworth, Rawle I, and Wang, Guijun. Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof. United States: N. p., 2000.
Web.
Hollingsworth, Rawle I, & Wang, Guijun. Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof. United States.
Hollingsworth, Rawle I, and Wang, Guijun. Sat .
"Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof". United States. https://www.osti.gov/servlets/purl/873072.
@article{osti_873072,
title = {Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof},
author = {Hollingsworth, Rawle I and Wang, Guijun},
abstractNote = {A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4-ylmethyl)trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2-dimethyl-1,3-dioxolan-4ylmethyl)trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Jan 01 00:00:00 EST 2000},
month = {Sat Jan 01 00:00:00 EST 2000}
}
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