Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof
Abstract
A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-1inked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.
- Inventors:
-
- Haslett, MI
- Issue Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- OSTI Identifier:
- 869659
- Patent Number(s):
- 5374773
- Assignee:
- Board of Trustees operating Michigan State University (East Lansing, MI)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
- DOE Contract Number:
- FG02-89ER14029
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- process; preparation; 4-dihydroxybutanoic; acid; salts; glucose; source; containing; 4-1inked; substituent; described; alkali; metal; hdyroxide; hydrogen; peroxide; convert; compound; useful; chemical; intermediate; naturally; occurring; fatty; acids; prepare; acid-gamma-lactone; furanone; particularly; stereoisomers; compounds; fatty acids; hydrogen peroxide; naturally occurring; alkali metal; fatty acid; source containing; glucose source; chemical intermediate; anoic acid; /999/
Citation Formats
Hollingsworth, Rawle I. Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof. United States: N. p., 1994.
Web.
Hollingsworth, Rawle I. Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof. United States.
Hollingsworth, Rawle I. Sat .
"Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof". United States. https://www.osti.gov/servlets/purl/869659.
@article{osti_869659,
title = {Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof},
author = {Hollingsworth, Rawle I},
abstractNote = {A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-1inked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Jan 01 00:00:00 EST 1994},
month = {Sat Jan 01 00:00:00 EST 1994}
}
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