Device to improve detection in electro-chromatography
Abstract
Apparatus and method for improving the resolution of non-pressure driven capillary chromatographic systems, and particularly for capillary electrochromatography (CEC) systems. By reducing the cross-sectional area of a packed capillary column by means of a second open capillary contiguous with the outlet end of a packed capillary column, where the packed capillary column has a cross sectional area of between about 2 and 5 times that of the open capillary column, the phenomenon of band broadening in the transition region between the open capillary and the packed capillary column, where the individual components of the mixture are analyzed, can be eliminated, thereby providing for a significant improvement in resolution and more accurate detection and analysis.
- Inventors:
-
- Livermore, CA
- Fremont, CA
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- OSTI Identifier:
- 873013
- Patent Number(s):
- 6068767
- Assignee:
- Sandia Corporation (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- device; improve; detection; electro-chromatography; apparatus; method; improving; resolution; non-pressure; driven; capillary; chromatographic; systems; particularly; electrochromatography; cec; reducing; cross-sectional; packed; column; means; contiguous; outlet; sectional; times; phenomenon; band; broadening; transition; region; individual; components; mixture; analyzed; eliminated; providing; significant; improvement; accurate; analysis; capillary column; transition region; accurate detection; significant improvement; individual components; individual component; /210/204/
Citation Formats
Garguilo, Michael G, Paul, Phillip H, and Rakestraw, David J. Device to improve detection in electro-chromatography. United States: N. p., 2000.
Web.
Garguilo, Michael G, Paul, Phillip H, & Rakestraw, David J. Device to improve detection in electro-chromatography. United States.
Garguilo, Michael G, Paul, Phillip H, and Rakestraw, David J. Sat .
"Device to improve detection in electro-chromatography". United States. https://www.osti.gov/servlets/purl/873013.
@article{osti_873013,
title = {Device to improve detection in electro-chromatography},
author = {Garguilo, Michael G and Paul, Phillip H and Rakestraw, David J},
abstractNote = {Apparatus and method for improving the resolution of non-pressure driven capillary chromatographic systems, and particularly for capillary electrochromatography (CEC) systems. By reducing the cross-sectional area of a packed capillary column by means of a second open capillary contiguous with the outlet end of a packed capillary column, where the packed capillary column has a cross sectional area of between about 2 and 5 times that of the open capillary column, the phenomenon of band broadening in the transition region between the open capillary and the packed capillary column, where the individual components of the mixture are analyzed, can be eliminated, thereby providing for a significant improvement in resolution and more accurate detection and analysis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Jan 01 00:00:00 EST 2000},
month = {Sat Jan 01 00:00:00 EST 2000}
}