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Title: Microfluidic devices and methods including porous polymer monoliths

Abstract

Microfluidic devices and methods including porous polymer monoliths are described. Polymerization techniques may be used to generate porous polymer monoliths having pores defined by a liquid component of a fluid mixture. The fluid mixture may contain iniferters and the resulting porous polymer monolith may include surfaces terminated with iniferter species. Capture molecules may then be grafted to the monolith pores.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1227358
Patent Number(s):
9201069
Application Number:
14/189,949
Assignee:
Sandia Corporation
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 Feb 25
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE

Citation Formats

Hatch, Anson V., Sommer, Gregory j., Singh, Anup K., Wang, Ying-Chih, and Abhyankar, Vinay. Microfluidic devices and methods including porous polymer monoliths. United States: N. p., 2015. Web.
Hatch, Anson V., Sommer, Gregory j., Singh, Anup K., Wang, Ying-Chih, & Abhyankar, Vinay. Microfluidic devices and methods including porous polymer monoliths. United States.
Hatch, Anson V., Sommer, Gregory j., Singh, Anup K., Wang, Ying-Chih, and Abhyankar, Vinay. Tue . "Microfluidic devices and methods including porous polymer monoliths". United States. https://www.osti.gov/servlets/purl/1227358.
@article{osti_1227358,
title = {Microfluidic devices and methods including porous polymer monoliths},
author = {Hatch, Anson V. and Sommer, Gregory j. and Singh, Anup K. and Wang, Ying-Chih and Abhyankar, Vinay},
abstractNote = {Microfluidic devices and methods including porous polymer monoliths are described. Polymerization techniques may be used to generate porous polymer monoliths having pores defined by a liquid component of a fluid mixture. The fluid mixture may contain iniferters and the resulting porous polymer monolith may include surfaces terminated with iniferter species. Capture molecules may then be grafted to the monolith pores.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 01 00:00:00 EST 2015},
month = {Tue Dec 01 00:00:00 EST 2015}
}

Works referenced in this record:

Process for producing a shaped product
patent, February 1999


Mobile monolithic polymer elements for flow control in microfluidic devices
patent, August 2004


Castable three-dimensional stationary phase for electric field-driven applications
patent, January 2005


Dialysis on microchips using thin porous polymer membranes
patent, September 2007


Histone deacetylase and methods of use thereof
patent, February 2009


Iniferter concept and living radical polymerization
journal, June 2000


Preparation of monolithic polymers with controlled porous properties for microfluidic chip applications using photoinitiated free-radical polymerization: Monolithic Polymers
journal, January 2002


Conduct-as-Cast Polymer Monoliths as Separation Media for Capillary Electrochromatography
journal, March 2001


Fabrication of porous polymer monoliths covalently attached to the walls of channels in plastic microdevices
journal, November 2003


Photografting and the Control of Surface Chemistry in Three-Dimensional Porous Polymer Monoliths
journal, March 2003


Microchip Dialysis of Proteins Using in Situ Photopatterned Nanoporous Polymer Membranes
journal, April 2004


Immobilized microfluidic enzymatic reactors
journal, November 2004


In situ fabrication of macroporous polymer networks within microfluidic devices by living radical photopolymerization and leaching
journal, January 2005


Surface Grafted Antibodies:  Controlled Architecture Permits Enhanced Antigen Detection
journal, November 2005


Patternable Protein Resistant Surfaces for Multifunctional Microfluidic Devices via Surface Hydrophilization of Porous Polymer Monoliths Using Photografting
journal, December 2006


Optimal Design of Microarray Immunoassays to Compensate for Kinetic Limitations: Theory and Experiment
journal, May 2006


Detection of Antigens in Biologically Complex Fluids with Photografted Whole Antibodies
journal, May 2006


Bio-particle separation using microfluidic porous plug for environmental monitoring
journal, January 2007


Photopatterning Enzymes on Polymer Monoliths in Microfluidic Devices for Steady-State Kinetic Analysis and Spatially Separated Multi-Enzyme Reactions
journal, September 2007


Controlled photopolymerization reactions: The reactivity of new photoiniferters
journal, January 2007