Vesicoureteral reflux in the primate IV: does reflux harm the kidney

Journal Article · Wed Sep 01 00:00:00 EDT 1982 · J. Urol.; (United States)

OSTI ID:6856099

Roberts, J A; Fischman, N H; Thomas, R

It has been said that vesicoureteral reflux causes renal scarring because of intrarenal reflux. We studied reflux in the monkey because of its similarity to man, especially in regard to the incidence of vesicoureteral reflux and chronic pyelonephritis. High pressure moderate grade reflux was produced and renal function followed by means of quantitative renal camera studies using /sup 131/I hippuran. There was no change in renal function from sterile reflux even when intrarenal reflux occurred. When, however, infection was introduced, renal function decreased. We concluded that sterile moderate vesicoureteral or intrarenal reflux does not harm the kidney.

• Research Organization: Department of Urology, Tulane Medical Center, New Orleans, Louisiana
• OSTI ID: 6856099
• Journal Information: J. Urol.; (United States), Vol. 128:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
KIDNEYS
BIOMEDICAL RADIOGRAPHY
URETERS
LAVAGE
HIPPURAN
IODINE 131
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CONTRAST MEDIA
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RADIOLOGY
URINARY TRACT
550601* - Medicine- Unsealed Radionuclides in Diagnostics