Sensitivity (SENS), specificity (SPEC) and predictive value (PV) of CCK cholescintigraphy: Follow-up of 99 surgically proven cases

Conference · Wed May 01 00:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:5975710

Fink-Bennett, D; DeRidder, P; Kolozsi, W; Gordon, R

To determine the SENS, SPEC and PV of CCK chole-scintigraphy (C) in the detection of acalculous biliary disease (ABD), the authors retrospectively evaluated the gallbladder ejection fraction response (GBEFR) to CCK in 99 post-cholecystectomy (Cx) patients (pts.) with pathologically proven ABD. The path criteria for chronic acalculous cholecystitis and/or the cystic duct syndrome included hypertrophy of the gallbladder wall (>1.5-2mm), diffuse hypertrophy of the muscularis propria with or without a concomitant mononuclear infiltration, serosal thickening, Aschoff-Rokitansky sinuses, foamy macrophages filling the tips of mucosal folds, yellow papillary nodule(s), fibrosis of the cystic duct, kinking or adhesions of the cystic duct seen at operation. The GBEFR to CCK indicative of ABD was defined as one in which the GBEFR was <35%. CCK C was performed after an overnight fast. Each pt. received 5 mCi of technetium-99m Hepatolite. When the GB maximally filled, .02 ..mu..g/kg CCK was administered (1-3 min.) I.V. Background corrected GBEFs were determined q.5 min. X4 by ratioing the pre-CCK GB cts minus post-CCK GB cts. to pre-CCK GB cts. The results of this clinical study are presented in this paper.

• Research Organization: William Beaumont Hospital, Royal Oak, MI
• OSTI ID: 5975710
• Report Number(s): CONF-850611-; TRN: 87-039226
• Journal Information: J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BILIARY TRACT
BIOMEDICAL RADIOGRAPHY
SCINTISCANNING
DIGESTIVE SYSTEM DISEASES
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RELIABILITY
PAIN
PATIENTS
SENSITIVITY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
MEDICINE
NUCLEAR MEDICINE
RADIOISOTOPE SCANNING
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