Increased susceptibility to radiofrequency radiation due to pharmacological agents

Journal Article · Thu Nov 01 00:00:00 EST 1984 · Aviat., Space Environ. Med.; (United States)

OSTI ID:5820584

Jauchem, J R; Frei, M R; Heinmets, F

The effects of chlorpromazine, methysergide, and propranolol on thermal responses to 2.8 GHz radiofrequency radiation were examined in anesthetized rats. During intermittent exposure at an average power density of 60 mW/sq cm (specific absorption rate, 14 W/kg), when colonic temperature was not allowed to rise above 39.5 C, none of the pharmacological agents had any significant effects on thermal responses. When exposure was continued until lethal temperatures resulted, animals which were administered chlorpromazine, methysergide, or propranolol exhibited significantly shorter survival times than saline-treated animals. Propranolol administration caused the greatest decrease in survival time and resulted in a significantly lower lethal temperature than that which occurred in saline-treated animals. 29 references.

• Research Organization: Trinity Univ., San Antonio, TX
• OSTI ID: 5820584
• Journal Information: Aviat., Space Environ. Med.; (United States), Vol. 55
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
RADIOWAVE RADIATION
BIOLOGICAL EFFECTS
BODY TEMPERATURE
CHLORPROMAZINE
PHARMACOLOGY
RADIOBIOLOGY
RATS
SENSITIZERS
AMINES
ANIMALS
AZINES
BIOLOGY
CENTRAL NERVOUS SYSTEM AGENTS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
DRUGS
ELECTROMAGNETIC RADIATION
HETEROCYCLIC COMPOUNDS
HYPNOTICS AND SEDATIVES
MAMMALS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PHENOTHIAZINES
PSYCHOTROPIC DRUGS
RADIATIONS
REAGENTS
RODENTS
TRANQUILIZERS
VERTEBRATES
560400* - Other Environmental Pollutant Effects