Special hazard review with control recommendations for 4,4'-methylenebis(2-chloroaniline)

Technical Report · Fri Sep 01 00:00:00 EDT 1978

OSTI ID:5637172

The report reviews current toxicity information on 4,4'-Methylenebis (2-chloroaniline) and makes control recommendations. 4,4'-Methylenebis(2-chloroaniline) has the formula C13H12C12N2. It is commercially important as a curing agent for diisocyanate-based polymers (polyurethanes) and epoxy resin systems. 4,4'-Methylenebis(2-chloroaniline) is used to vary the hardness, flexibility, and impact strength of these products. 4,4'-Methylenebis(2-chloroaniline) has been manufactured commercially in the U.S. since 1956. Above 200 C, 4,4'-Methylenebis(2-chloroaniline), releases irritant and toxic vapors (primarily ortho-chloroaniline). NIOSH estimated through a national survey that in the early 1970's approximately 55,000 U.S. workers were potentially exposed to 4,4'-Methylenebis(2-chloroaniline). The majority of these workers were employed in small-to-medium sized establishments where occupational health services may not have been readily available. This review provides an examination of information available in 1973 and a more detailed presentation of recent studies along with recommendations for control of workplace exposures to 4,4-Methylenebis(2-chloroaniline).

• Research Organization: National Inst. for Occupational Safety and Health, Cincinnati, OH (USA)
• OSTI ID: 5637172
• Report Number(s): PB-297822
• Country of Publication: United States
• Language: English

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HAZARDOUS MATERIALS
INDUSTRIAL MEDICINE
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570000 - Health & Safety