Intake and Excretion Patterns of Naturally Occurring Radium-226 in Humans
The dietary intake and the urinary and fecal excretion of naturally occurring ²²⁶Ra and ²²⁶Ra balances were determined in man under strictly controlled dietary conditions. These provided the basis for calculating the ²²⁶Ra balances. These balance studies were carried out during a low calcium intake, during the addition of different amounts of calcium given as calcium gluconate, and during the intake of milk. ²²⁶Ra balances were also determined during conditions that affect the metabolism of calcium: during intravenous infusions of stable strontium, during infusions of AC TH, and during total calorie starvation. During a low calcium irtake of an average of 243 mg/ day, the urinary /sup 226/Ra excretion averaged 0.016 pCi/day, during a calcium intake of 1300 mg or 2600 mg/day, given as calcium gluconate, the urinary ²²⁶Ra excretion did not increase, while during supplementation of she diet with milk the urinary /sup 226/Ra excretion increased. On all calcium intakes the urinary ²²⁶Ra excretion averaged 3% of the total excretion except that it was 12% on milk intake. The major pathway of ²²⁶Ra excretion was via the intestine and the ²²⁶Ra balances were in equilibrium under all study conditions. There was no correlation between the urinary ²²⁶Ra and the urinary calcium excretion. (auth)
- Research Organization:
- Veterans Administration Hospital, Hines, IL
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-29-005366
- OSTI ID:
- 4386494
- Journal Information:
- Radiation Research, Vol. 56, Issue 2; Other Information: Orig. Receipt Date: 30-JUN-74; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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