Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu[subscript 2] Receptor Agonist
Journal Article
·
· Journal of Medicinal Chemistry
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- INDUSTRY
- OSTI ID:
- 1239424
- Journal Information:
- Journal of Medicinal Chemistry, Vol. 58, Issue (18) ; 09, 2015; ISSN 0022-2623
- Country of Publication:
- United States
- Language:
- ENGLISH
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