Nucleic acids encoding antifungal polypeptides and uses thereof
- Granger, IA
- Kyiv, UA
- Norwalk, IA
- Elliott City, MD
- Avondale, PA
- Port Deposit, MD
- Des Moines, IA
- Richmond, CA
- Johnston, IA
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
- Research Organization:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC02-05CH11231
- Assignee:
- Pioneer Hi-Bred International, Inc. (Johnston, IA); E.I. du Pont de Nemours and Company (Wilmington, DE); The Regents of the University of California (Oakland, CA)
- Patent Number(s):
- 7,825,294
- Application Number:
- US Patent Application 12/503,952
- OSTI ID:
- 1014929
- Country of Publication:
- United States
- Language:
- English
Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
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journal | May 1998 |
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