Why do we get Alzheimer's disease?

Multimedia · Mon Oct 02 00:00:00 EDT 2006

OSTI ID:987523

Wyss-Coray, Tony

Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.

• Research Organization: SLAC (SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States))
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: AC02-76SF00515
• OSTI ID: 987523
• Resource Relation: Conference: SLAC Public Lecture Series, SLAC National Accelerator Laboratory, Menlo Park, California, presented on October 02, 2006
• Country of Publication: United States
• Language: English

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