Electrochemical methods for generation of a biological proton motive force

Patent · Tue Dec 02 00:00:00 EST 2008

OSTI ID:985723

Zeikus, Joseph Gregory ^[1]; Shin, Hyoun S ^[2]; Jain, Mahendra K ^[3]

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1. Okemos, MI
2. Lansing, MI
3. Lexington, KY

Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.

• Research Organization: Michigan State Univ., East Lansing, MI (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: FG02-93ER20108
• Assignee: Board of Trustees of Michigan State University (East Lansing, MI)
• Patent Number(s): 7,459,223
• Application Number: 11/088,278
• OSTI ID: 985723
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES