Variants of beta-glucosidases

Patent · Tue Aug 19 00:00:00 EDT 2008

OSTI ID:985366

Fidantsef, Ana ^[1]; Lamsa, Michael ^[1]; Clancy, Brian Gorre ^[2]

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1. Davis, CA
2. Elk Grove, CA

The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

• Research Organization: National Renewable Energy Laboratory (NREL), Golden, CO (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC36-98GO10337
• Assignee: Novozymes, Inc. (Dan's, CA)
• Patent Number(s): 7,413,888
• Application Number: 10/836,063; TRN: US201016%%1950
• OSTI ID: 985366
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
AMINO ACIDS
INVENTIONS
NUCLEIC ACIDS
NUCLEOTIDES
VECTORS