skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Antimocrobial Polymer

Patent ·
OSTI ID:879747
 [1];  [2];  [3]
  1. Utica, OH
  2. Walnut Creek, CA
  3. Columbus, GA
+ Show Author Affiliations

A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, (ii) an antimicrobial agent selected from quaternary ammonium compounds, gentian violet compounds, substituted or unsubstituted phenols, biguanide compounds, iodine compounds, and mixtures thereof, and (iii) a crosslinking agent containing functional groups capable of reacting with the amino groups. In one embodiment, the polymer is a polyamide formed from a maleic anhydride or maleic acid ester monomer and alkylamines thereby producing a polyamide having amino substituted alkyl chains on one side of the polyamide backbone; the crosslinking agent is a phosphine having the general formula (A)3P wherein A is hydroxyalkyl; and the antimicrobial agent is chlorhexidine, dimethylchlorophenol, cetyl pyridinium chloride, gentian violet, triclosan, thymol, iodine, and mixtures thereof.

Research Organization:
Midwest Research Institute, Kansas City, MO (United States)
DOE Contract Number:
AC36-98GO10337
Assignee:
Michigan Biotechnology Institute (Lansing, MI)
Patent Number(s):
US 6,939,554
Application Number:
10/068054
OSTI ID:
879747
Country of Publication:
United States
Language:
English

References (17)

Synthesis and in Vitro Degradation of New Polyvalent Hydrazide Cross-Linked Hydrogels of Hyaluronic Acid journal September 1997
Polyacrylic polyhydrazides as reagents for detection of glycoproteins journal August 1989
Polyacrylhydrazido-agarose: Preparation via periodate oxidation and use for enzyme immobilization and affinity chromatography journal October 1981
Binding of the basement-membrane glycoprotein laminin to glycosaminoglycans. An affinity-chromatography study journal December 1981
Immobilization of protein ligands with methyl vinyl ether-maleic anhydride copolymer journal April 1992
Immobilization of Saccharides and Peptides on 96-Well Microtiter Plates Coated with Methyl Vinyl Ether–Maleic Anhydride Copolymer journal June 1998
Immobilised phosphines incorporating the chiral biopolymers chitosan and chitin journal January 1994
Application of tris(hydroxymethyl)phosphine as a coupling agent for alcohol dehydrogenase immobilization journal April 1996
Water-soluble tris(hydroxymethyl)phosphine complexes with nickel, palladium, and platinum. Crystal structure of [Pd{P(CH2OH)3}4].cntdot.CH3 journal July 1992
New polyurethane compositions able to bond high amounts of both albumin and heparin journal January 1995
Oriented immobilization of periodateoxidized monoclonal antibodies on amino and hydrazide derivatives of eupergit C journal February 1990
Immobilization of glycoconjugates by their oligosaccharides: Use of hydrazido-derivatized matrices journal November 1990
P(CH2OH)3? a new coupling reagent for the covalent immobilisation of enzymes journal January 1994
Preparation of High Capacity Affinity Adsorbents Using New Hydrazino-Carriers and Their Use for Low and High Performance Affinity Chromatography of Lectins1 journal April 1986
Synthesis of large haptenic compounds having a common functional group that permits covalent linkage to proteins, cell surfaces, and adsorbents journal March 1973
The derivatization of oxidized polysaccharides for protein immobilization and affinity chromotography journal March 1976
Preparation of surface-modified albumin nanospheres journal April 1997

Similar Records

Antimicrobial Polymer
Patent · Tue Sep 28 00:00:00 EDT 2004 · OSTI ID:879747
Antithrombogenic Polymer Coating.
Patent · Tue Jan 21 00:00:00 EST 2003 · OSTI ID:879747
+1 more
Crosslinked Polyamide
Patent · Tue Jun 04 00:00:00 EDT 2002 · OSTI ID:879747
+1 more

Related Subjects