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Title: SNP-VISTA: An Interactive SNPs Visualization Tool

Journal Article · · BMC Bioinformatics

Recent advances in sequencing technologies promise better diagnostics for many diseases as well as better understanding of evolution of microbial populations. Single Nucleotide Polymorphisms(SNPs) are established genetic markers that aid in the identification of loci affecting quantitative traits and/or disease in a wide variety of eukaryotic species. With today's technological capabilities, it is possible to re-sequence a large set of appropriate candidate genes in individuals with a given disease and then screen for causative mutations.In addition, SNPs have been used extensively in efforts to study the evolution of microbial populations, and the recent application of random shotgun sequencing to environmental samples makes possible more extensive SNP analysis of co-occurring and co-evolving microbial populations. The program is available at http://genome.lbl.gov/vista/snpvista.

Research Organization:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE Director. Office of Science. Office of Biological andEnvironmental Research
DOE Contract Number:
DE-AC02-05CH11231
OSTI ID:
878705
Report Number(s):
LBNL-58131; R&D Project: VGTLID; BnR: KP1102010; TRN: US200611%%412
Journal Information:
BMC Bioinformatics, Vol. 6; Related Information: Journal Publication Date: 12/08/2005
Country of Publication:
United States
Language:
English