Recombinant HT.sub.m4 gene, protein and assays

Lim, Bing; Adra, Chaker N; Lelias, Jean-Michel

Title: Recombinant HT.sub.m4 gene, protein and assays

Patent · Mon Jan 01 00:00:00 EST 1996

OSTI ID:870590

Lim, Bing ^[1]; Adra, Chaker N ^[2]; Lelias, Jean-Michel ^[3]

Dorcester, MA
Boston, MA
Toulouse, FR

The invention relates to a recombinant DNA molecule which encodes a HT.sub.m4 protein, a transformed host cell which has been stably transfected with a DNA molecule which encodes a HT.sub.m4 protein and a recombinant HT.sub.m4 protein. The invention also relates to a method for detecting the presence of a hereditary atopy.

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Research Organization:: Univ. of Chicago, IL (United States)

DOE Contract Number:: FG02-86ER60408

Assignee:: Beth Israel Hospital Boston (Boston, MA)

Patent Number(s):: US 5552312

OSTI ID:: 870590

Country of Publication:: United States

Language:: English

References (12)

A major gene for allergy — fact or fancy? Marsh, David G.; Meyers, Deborah A. Nature Genetics, Vol. 2, Issue 4 https://doi.org/10.1038/ng1292-252	journal	December 1992
Fc Receptors Ravetch, J. V.; Kinet, J. P. Annual Review of Immunology, Vol. 9, Issue 1 https://doi.org/10.1146/annurev.iy.09.040191.002325	journal	April 1991
Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E. Kinet, J. P.; Blank, U.; Ra, C. Proceedings of the National Academy of Sciences, Vol. 85, Issue 17 https://doi.org/10.1073/pnas.85.17.6483	journal	September 1988
Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor Shirakawa, Taro; Li, Airong; Dubowitz, Michael Nature Genetics, Vol. 7, Issue 2 https://doi.org/10.1038/ng0694-125	journal	June 1994
Atopy and Fc receptors: mutation is the message? Ravetch, Jeffrey V. Nature Genetics, Vol. 7, Issue 2 https://doi.org/10.1038/ng0694-117	journal	June 1994
LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q Cookson, WilliamO. C. M.; Faux, JenniferA.; Sharp, PamelaA. The Lancet, Vol. 333, Issue 8650 https://doi.org/10.1016/S0140-6736(89)92687-1	journal	June 1989
The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor. Küster, H.; Zhang, L.; Brini, A. T. Journal of Biological Chemistry, Vol. 267, Issue 18 https://doi.org/10.1016/S0021-9258(18)42344-7	journal	June 1992
Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells Ra, C.; Jouvin, M. H.; Kinet, J. P. Journal of Biological Chemistry, Vol. 264, Issue 26 https://doi.org/10.1016/S0021-9258(19)84829-9	journal	September 1989
Determination of the sequence coding for the β subunit of the human high-affinity IgE receptor Maekawa, Kazuhiko; Imagawa, Noriko; Tanaka, Yoshiaki FEBS Letters, Vol. 302, Issue 2 https://doi.org/10.1016/0014-5793(92)80430-O	journal	May 1992
Allergy by mutation Davies, Kevin Nature, Vol. 369, Issue 6480 https://doi.org/10.1038/369506a0	journal	June 1994
Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions. Adra, C. N.; Lelias, J. M.; Kobayashi, H. Proceedings of the National Academy of Sciences, Vol. 91, Issue 21 https://doi.org/10.1073/pnas.91.21.10178	journal	October 1994
Maternal inheritance of atopic IgE responsiveness on chromosome 11 q Cookson, W. O. C. M.; Young, R. P.; Sandford, A. J. The Lancet, Vol. 340, Issue 8816 https://doi.org/10.1016/0140-6736(92)91468-N	journal	August 1992

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recombinant
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method
detecting
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atopy
recombinant dna
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host cell
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/435/999/

Title: Recombinant HT.sub.m4 gene, protein and assays

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References (12)

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