Biosensor and chemical sensor probes for calcium and other metal ions

Patent · Mon Jan 01 00:00:00 EST 1996

OSTI ID:870326

Vo-Dinh, Tuan ^[1]; Viallet, Pierre ^[2]

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1. Knoxville, TN
2. Perpignan, FR

The present invention relates to chemical sensor and biosensor probes for measuring low concentration of metals and metal ions in complex samples such as biological fluids, living cells, and environmental samples. More particularly the present invention relates to a gel-based Indo-1 and Fura-2 chemical sensor probes for the measurement of low concentrations of calcium, cadmium, magnesium and the like. Also disclosed is a detector device using the sensors of the present invention.

• Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
• DOE Contract Number: AC05-84OR21400
• Assignee: Martin Marietta Energy Systems, Inc. (Oak Ridge, TN)
• Patent Number(s): US 5496522
• OSTI ID: 870326
• Country of Publication: United States
• Language: English

Related Subjects

biosensor
chemical
sensor
probes
calcium
metal
relates
measuring
concentration
metals
complex
samples
biological
fluids
living
cells
environmental
particularly
gel-based
indo-1
fura-2
measurement
concentrations
cadmium
magnesium
disclosed
detector
device
sensors
living cells
environmental sample
chemical sensor
environmental samples
biological fluids
sensor probe
biological fluid
sensor probes
detector device
/422/436/999/